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Fruit bowl by happencstance

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Fish and Tomatoes

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Split Pea Soups


Fresh Tuna and Tofu Sauce

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Prostate Diet Cookbook
Prostate Diet Cookbook

$16.76 Harbor Press

Green Tea Shown to Prevent Prostate Cancer

First Clinical Study Shows 90 Percent Efficacy in Men with Pre-malignant Lesions

April 20, 2005. Anaheim, Calif. - After a year's oral administration of green tea catechins (GTCs), only one man in a group of 32 at high risk for prostate cancer developed the disease, compared to nine out of 30 in a control, according to a team of Italian researchers from the University of Parma and University of Modena and Reggio Emilia led by Saverio Bettuzzi, Ph.D.

Their results were reported here today at the 96 th Annual Meeting of the American Association for Cancer Research.

"Numerous earlier studies, including ours, have demonstrated that green tea catechins, or pure EGCG (a major component of GTCs), inhibited cancer cell growth in laboratory models," Bettuzzi explained. "We wanted to conduct a clinical trial to find out whether catechins could prevent cancer in men. The answer clearly is yes."

Earlier research demonstrated primarily that green tea catechins were safe for use in humans. Bettuzzi and his colleagues had found that EGCG targets prostate cancer cells specifically for death, without damaging the benign controls. They identified Clusterin, the most important gene involved in apoptosis, or programmed cell death in the prostate, as a possible mediator of catechins action. "EGCG induced death in cancer cells, not normal cells, inducing Clusterin expression" said Bettuzzi.

To gauge susceptibility for prostate cancer among their research subjects, the team of Italian scientists recruited men with high-grade prostatic intraepithelial neoplasia - premalignant lesions that presage invasive prostate cancer within one year in nearly a third of cases and for which no treatment was given.

Eligible men were between 45 and 75 years of age. Vegetarians and men consuming green tea or derived products, or those taking anti-oxidants or following anti-androgenic therapy were excluded.

Of the 62 volunteers, 32 received three tablets per day of 200 mg each GTCs; the remainder were given a placebo. Follow-up biopsies were administered after six months and again at one year. Only one case of prostate cancer was diagnosed among those receiving 600 mg daily of GTCs, while nine cases were found in the untreated group. The 30 percent incidence rate among controls is consistent with previous findings, as was the absence of significant side effects or adverse reactions.

The interest in green tea catechins and other polyphenols - antioxidants found in many plants that give some flowers, fruits and vegetables their coloring - derives from traditional Chinese medicine, and the observation of lower cancer rates among Asian populations.

Bettuzzi observed that the Mediterranean diet is rich in vegetables, and lower rates of prostate cancer are found in that region, as well.

The 600 mg-per-day dosage of caffeine-free, total catechins (50 percent of which is EGCG) given to participants in the Italian study is one or two times the amount of green tea consumed daily in China, where ten to 20 cups a day is normal.

"We still don't know enough about the biological processes leading to prostate cancer," Bettuzzi noted. "The only thing we know for sure is that prostate cancer is diffuse, related to age and more prevalent in the West. Thus, prevention could be the best way to fight it. Although our follow-up will continue for up to five years, a larger, confirmatory study is needed."

Even so, Bettuzzi hints at the exciting prospect of using green tea catechins as a prophylactic against prostate cancer in men believed to be at higher risk, such as the elderly, African-Americans, and those with a family history of prostate cancer.

Tomato oil in trial to help men with high-grade PIN (precancerous prostate changes) Nov 8, 2004

Plastics in food containers may stimulate prostate cancer in men taking hormonal therapy. Jan 3 2005

Strong-flavored onions show promise for fighting cancer Oct. 2004. Although milder onions are popular, the bitter and more pungent onions may be healthier, according to researchers at Cornell University.
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Overstuffed: Eating out can blind us September 27, 2004. People routinely underestimate the amount of fat and calories in restaurant meals, sometimes by very significant amounts.... Full story

Earlier Food News

"Two Studies Compare Levels of Contaminants in Farmed versus Wild Salmon" Fall 2002

Magic Bullet Supplements Unlikely to Prevent Cancer Whole Foods Best Protection March 6, 2000. Cancer-fighting substances in fruits, vegetables, whole grains and beans, pills and supplements work together in complex ways. Vitamin pills cannot make up for the vitamins, minerals and phytochemicals found in these foods, researchers say. Full story

Greens, B12 May Lower Cancer Risk Eating three times the recommended daily intake of folate and vitamin B12 may lower the risk factors for cancer by protecting your DNA, an Australian study claims. Folate-rich foods include leafy green vegetables and wholegrains. B12 is found in meat, chicken, fish, liver and kidneys or in vegetarian supplement form. Full story

Fruits and Vegetables Prevent Osteoporosis In Men
April 2, 1999.Two different bone conditions may afflict men who have prostate cancer -- osteoporosis (or bone loss) caused or made worse by hormonal blockade; and spread of cancer to the bones. Drugs may be needed to combat osteoporosis, but diet may play a part in protecting against it. A new look at lifetime diets ofparticipants in the Framington Heart Study found that for both men and women, lifelong dietary intake of potassium, magnesium and fruits and vegetables affected bone strength in old age.
Full story

Broccoli organic seed supplies, sprouting methods

Green Tea ABC newsman George Orick in Indonesia

For healthy recipes check out Potluck and Lenny Hirsch's recipes.
And you might like to try the Ratattouille recipe at AARP's online magazine or their Spicy Salsa Chicken Grill (a diabetic recipe).

photos from: stockxchange

Lenny's Cookbook Eat bright colored veggies. Peppers photo by R Young.

More Food News

Selenium, Lycopene, Vit E: Antioxidant Blood Levels Key to a Genetic Prostate Cancer Risk March 15 2005

Lycopene plus vitamin E Slows Prostate Cancer in Mice Oct 2004

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